Define and differentiate synaptic integration: spatial vs temporal summation; how inputs shape output.

Define and differentiate synaptic integration: spatial vs temporal summation; how inputs shape output.

• A. Spatial summation combines inputs from different synapses to increase depolarization.
• B. Temporal summation combines rapid inputs from the same synapse; Inhibition has no effect.
• C. Inhibition always enhances the chance of reaching threshold.
• D. Spatial summation integrates inputs across different synapses; temporal summation integrates rapid inputs from the same synapse; inhibition reduces the probability of reaching threshold; net effect determines AP generation.

Answer: (D)